@southtexas I'm so interested in your comment -I am a 66 yr woman in Boston area- you have never been able to go lower than 5mg ? have you relapsed in the 4 year time period you describe ? I'm only 2 months into the PMR journey My doctors are at MGH , which was a site for the sarilumab trial . Luckily i found a rheum consult in 4 weeks after being seen by PCP, BUT, sadly today I feel absolutely worse after increased dose ; 20mg only 3days- new dose after rheumatologist consult, from 10mg+5mg (26days-prescribed by PCP). I've been musing that I feel i either picked a "good" time to get PMR ( HA ! or it picked me ) or maybe next year would be better, given this brand new approval for Kevzara in PMR. When i was spreading awareness in my family , turns out my cousin ( 10 yrs older and a male) had PMR 4 yrs ago !