I had the IOVERA injection 2 weeks prior to TKR. Despite being touted as painless the pain, whether from an inept anesthesiologist I don’t know, but I about passed out twice and I have a very high pain tolerance. Moving forward 4.5 months my leg from mid calf to upper thigh alternates between an odd numbness to intense pain if it’s touched. The knee itself is an odd mixture of pain and numbness. I am so sorry I let my ortho convince me this would aid in a “more pain free recovery”. My surgeon doesn’t seem terribly concerned either.