Same plan for me, I injected my first dose yesterday, I’ve been on around 5 ml of Pred for over 4 years. I did have a slight reaction to the Kevzara, felt ache and had 101 fever for about 3 hours, today I feel normal. That’s all I know for now.

Started Kevzara200 last Sunday.Get every two weeks. For now 10 Prednisone and 15 Methotrexate. Will start tapering in one week. Anxious about serious side effects of Sarilumab.

Lab after 8 weeks

I’m also scheduled to start Kevzara next week. Praying that it will help me to reduce my prednisone (currently ant 17.5 and holding). Blessings!

I appreciate this thread, since Kevzara is so new it is important for those of us on it to share our experiences.

Personally, I wouldn't take the chance on any new drug due to my PMR being a direct result of the Covid Booster, (last September 2022) which was too new in its infancy to know the dangers! Never again. Of course, that is just my opinion. I tolerate Prednisone very well and tapering from 15 to 12.5 did not even phase me except the fatigue continues. I feel 100% better getting a second opinion from a great Rheumatologist. I will be on Prednisone for a while, another 18 months if not forever. Important to note and share that my blood sugar has dropped almost one point since I started back on Prednisone in March 2023. SIide effects can increase A1-C levels dramatically, however, it improved mine. I went from a 6.1 down to a 5.4 level. Hasn't been that low in 3-5 years. So Prednisone is actually helping me in more ways than one. I wish you the best results possible on this journey. Everyone is different and presents differently. I get so much from everyone's posts so please do keep sharing with everyone! It certainly helps to know we don't have to go it alone! Deb

Has anyone been on Kevzara for more than a couple of months? Would really be helpful to know how it worked for you. I took my first dose but still am apprehensive.

My rheumatologist seemed to feel that Kevzara and Actemra were similar and that it did not matter which was used as I taper off Prednisone. Both suppress the IL-6 immune system pathway. I'm on Actemra only because my medical provider gets it more cheaply, so they prefer its use. My guess is that the Kevzara side effects are far less than Prednisone; Kevzara is highly targeted and is not a hormone, so likely tolerated far better than Prednisone.

By the way I’m up here in the Pacific Northwest, Oregon Westside and suburbs!

Worth teading asbit looks like PMR could bevGBS in disguise !