Well, guess I just learned another thing about 4 yrs of exemestane - trigger thumb for the last year; very painful and unexplained sudden appearance. No one - ortho, Onco or primary suggests side effect of the drug. So much they don’t seem to know; unsure they care - it’s always ‘just be glad’….Also now debilitating pain in hips, toes - though I remain active not sedentary. Long for the day they listen, connect the dots, do research related to one size fits all dosage of these drugs.