← Return to Aromatase Inhibitors: Did you decide to go on them or not?

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I don't have a link for that article but will post it if I come upon it again. I never did find an explanation for why he cited the predicted benefit of aromatase inhibitors at such a low number. But it really depends on the composition of the statistical universe that he was looking at.

As I noted, I had a low OncotypeDX score so already had, again if the OncotypeDX is a valid and powerful model, a single digit risk of recurrence anyway. That's why being well informed about exactly what one is dealing with is so important because the decisions sometimes need to be made on essentially very short notice. But at least with aromatase inhibitors one can at least try them. I contrast that with chemo and radiation decisions which can have permanent consequences and sometimes have to be made before one understands really what they entail. I continue to hope that everyone dealing with the wily cancer foe gets at least second opinions every step of the way.

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Agree, and I would add that my uneducated guess is that the side affects of AI's, Tamoxifen would mimic menopause and mine was absolute hell. If you had a rough time with that like me then this therapy would be almost just like it or maybe worse. I chose to turn them down no matter what. I also turned down the Oncotype test as well, simply because I knew I would not take them, making the test a moot point. Had they found cancer in my lymph node(s) I knew I was a 100% I wanted chemo. That was my plan and I was sticking with it. Thankfully they did not and my pathology turned out great. Based on the algorithms my benefit of AI"s was in the 0.4 to 1.4 range over 10 years. My belief is that a lot of woman take them because they are told to and I don't think they are doing themselves any favors by not finding out exactly benefit vs toxicities and quality of life.