kugrad1975: As I understand it, your biopsy material is good for a year so you may want to have a Decipher test using the biopsy material to test aggressiveness. Maybe the Oncotype DX score can be used for prostate spread issues as well but I thought it was used more for breast cancer. My psa jumped from the earlier years of 1-4 to 6.8, then 8 then 10.2 in a one and a half year period. A prostate MRI really helped me to decide on a biopsy. I had 3+4 Gleason and was 69 when I made my decision for narrow margin radiation. I just turned 70 and have had 5 treatments of radiation finishing in February of this year. For me, I did not want to think about "it" getting worse in the short term, daily, weekly or monthly. I was looking for some sort of relief for a longer period of time with good quality of life.