I am a 76 year old woman who has been feeling very fatigued since my arthritis pain has gotten worse about 6 months ago. I also have a herniated lumbar disc which causes pain and numbness down my left leg into my feet. My legs feel heavy and tired. I read that pain can cause exhaustion. When I take a 50 mg Tramadol, the pain vanishes and I feel more energetic. I take it a couple of times of week when I have yard work or house work to do. With the Tramadol, I can work for 3 hours without pain or fatigue. Without Tramadol, I would be sitting inside working a jigsaw puzzle.