I want to reply to this answer again I do think it has reduced fatigue and post-exertion malaise. Thinking back I have less crash days where I'm so crashed out I can barely keep my eyes open and everything looks White. I still have to function as a single parent so I'm awake for it. I haven't had what I call crash white out day for about 2 and 1/2 3 weeks and I've been on LDN for about a month or less slowly titrating from 0.5 mg I think I got up to 2.5 mg which I know is fast for a lot of people until I ran out so I'm waiting for my new order. I was taking the capsules with cellulose I decided to go for the liquid to see if the cellulose was causing some of the heavy sweating all day hot flashes and cold flashes