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@imbimbo

Given the relatively low PSA I would first get a second opinion on the biopsies slides. Fours and threes are subjectively read. I found out that my 3+4 was 3+3 after John Hopkins studied them. My PSA is 5.49 and I am 70 1/2. But to answer your question my urologist has me under active surveillance and he suggested I first try the HIFU. It can be repeated and all other options remain on the table if it does not do its job. It probably depends upon how many lesions are found. Also I had a 3T multiparametric MRI where they located my two lesions (9mm and 4mm). I would get an MRI done and then discuss the ablation option with your urologist.

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Replies to "Given the relatively low PSA I would first get a second opinion on the biopsies slides...."

Also if you get the MRI they can biopsy only the lesions by fusing the MRI image to the real time ultrasound image.

@imbimo, thanks for the insight! To give you a little more of a background on my diagnosis, I had the TURP procedure performed in March because of BPH. A biopsy of the tissue from that procedure revealed that I had prostate cancer and the Gleason score 3+4=7. I had an appointment with my urologist and we discussed the options which at the time I felt like I just wanted to get the cancer out and scheduled the radical prostatectomy. In the meantime he scheduled an MRI in which showed no lesions and a T2. My PSA had never been higher than 3.99. My surgery is scheduled for next week May 9th and I’m confused as to which way to turn. I’m relatively young and want to just get rid of the cancer and yet its a significant surgery and I’m not looking forward to the longer rehab.