I was never on Prednisone because nobody diagnosed me until 2 years into this. I suspect it is too late now, even if I wanted to take it. I survived on massive doses of Ibuprofen which so far has not caused me additional problems, but it does concern me. I'm trying to go to Tyelonol and wondering how many you have to take to function and if it has caused you any additional problems. Also trying to be better (I'm not bad) about diet.