I was diagnosed with stage 3 pancreatic cancer in jan 2021. I have had Whipple surgery with msv reconstruction followed by 12 treatments of Folfirinox. Dietician guidelines for Creon were:
Take 300-1800 units per gram of fat, or 500-2500 units per kg of body weight per meal. Too little Creon results in gas, bloating and diarrhea. Sufficient Creon usually results in darker stools.
I am currently taking 125,000-175,000 units immediately prior to eating a meal with generally good results - no gas, bloating or diarrhea, although still no change in stool colour. I was assured it is almost impossible to overdose on Creon, so to continue to increase until stools darken to normal colour. Recently, they had me try to reduce the amount I was taking but that resulted in gas and diarrhea returning. I have had to adjust dose as I slowly regained weight. Latest discussion indicated stool colour can also be impacted by surgery, so the go more on how I am feeling than colour of stool. All the best to you!