I wanted a cure from the pain, not opioids. A study I found from the Cleveland Clinic suggests 300 mg of CoQ10 and 20 mg of PQQ daily. Although I still have neuropathy, the pain is gone. Before this it felt like I was walking on hot coals. It’s not overnight, but th pain in my hands and a lot of the pain in my feet was gone after about 3 months. I’ve been taking these for a year. My feet are still mostly numb, but they are pain free.