I have never done a Chat room like this, but I am compelled by my own experience to join and hope that the medical community takes this seriously. I began to experience neuropathy in my feet with rapid onset after cardiac ablation surgery. I had been taking 40mg pantoprazole daily prior to surgery , and the cardiologist increased that to 80mg for 8 weeks following surgery. I did not connect my onset of neuropathy with the increase in protonix until a few months later (after extensive neuro evaluation ) when I went off my protonix for a few days when I had a gap in my scrip. I noticed a clear receding of the neuropathy during this gap (in which I switched to H2). Then I began to experiment with intermittent switching between protonix and H2. It was darn clear that the protonix was the culprit in my neuropathy. Then the epiphany that the onset coincided with the increase to 80mg a few months earlier. I am trying to figure out how to move away permanently from PPI's. This chat room is helping me.