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Low Dose Naltrexone and Prednisone for PMR?

Polymyalgia Rheumatica (PMR) | Last Active: Aug 4 6:29am | Replies (85)
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@pkalkstein

Thanks @suetex! I used MSM in the past and I still have some. Didn't know it was good for this purpose, but will try it, although the horse is already out of the barn.

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Replies to "Thanks @suetex! I used MSM in the past and I still have some. Didn't know it..."
DadCue | @dadcue | Apr 29, 2023

@suetex might be on to someting. WebMD doesn't have too many negatives about MSM
https://www.webmd.com/vitamins-and-supplements/msm-methylsulfonylmethane-uses-and-risks#:~:text=Don't%20take%20any%20chances,you%20are%20pregnant%20or%20breastfeeding.
Maybe I will try some too. However, my biologic is downregulating IL-6 already.

I'm sorry you are having a flare. It is incredible how many people have flares when they get down to approximately 7 mg of prednisone. It is interesting that approximately 7 mg of prednisone corresponds to the amount of cortisol the body needs daily to regulate inflammation and other bodily functions. When you start to go much lower than 7 mg the body seems to go crazy and can't maintain its homeostasis.
https://www.ncbi.nlm.nih.gov/books/NBK538239/

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