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I completely agree with all of your comments regarding the importance of hydration. Unfortunately, my husband wouldn't keep up with the daily intake of fluids that are needed. He is now in the hospital, recovering from dehydration and the inability to eat and keep anything down. He is getting better slowly. He just started getting fed through a feeding tube to get nutrients back in his body.

His Folfironox is on hold for a few weeks and we will probably need to proceed with a reduced dosage.

I plan on supplementing it with High Dose Intraveneous Vitamin C and the Care Oncology Protocol of off-label drugs to starve his cancer. (Metformin, Doxycycline, Mebendazole and Atorvastatin. )

Our next step, however, is getting his strength back from lack of eating and dehydration.

Editor's Note:
From Mayo Clinic - High-dose vitamin C: Can it kill cancer cells? https://www.mayoclinic.org/diseases-conditions/cancer/expert-answers/alternative-cancer-treatment/faq-20057968

Interest in using very high doses of vitamin C as a cancer treatment began as long ago as the 1970s when it was discovered that some properties of the vitamin may make it toxic to cancer cells. Initial studies in humans had promising results, but these studies were later found to be flawed.

Subsequent well-designed, randomized, controlled trials of vitamin C in pill form found no such benefits for people with cancer. Despite the lack of evidence, some alternative medicine practitioners continue to recommend high doses of vitamin C for cancer treatment.

More recently, vitamin C given through a vein (intravenously) has been found to have different effects than vitamin C taken in pill form. This has prompted renewed interest in the use of vitamin C as a cancer treatment.

There's still no evidence that vitamin C alone can cure cancer, but researchers are studying whether it might boost the effectiveness of other cancer treatments, such as chemotherapy and radiation therapy, or reduce treatment side effects.

There are still no large, controlled clinical trials that have shown a substantial effect of vitamin C on cancer, but some preliminary studies do suggest there may be a benefit to combining standard treatments with high-dose IV vitamin C. Until clinical trials are completed, it's premature to determine what role vitamin C may play in the treatment of cancer.
Karthik Giridhar, M.D.

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Replies to "I completely agree with all of your comments regarding the importance of hydration. Unfortunately, my husband..."

Did he actually start the Care Oncology protocol? How was it to get started? Do they assign you to an MD/oncologist? Although they are based in the UK, can they prescribe the meds you mentioned for here in the U.S.?
I guess finally, what has his experience been?