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DiscussionHow important is it to treat flare-ups and how do you know when?
MAC & Bronchiectasis | Last Active: Apr 27, 2023 | Replies (16)Comment receiving replies
Replies to "Has anyone had a side effect when taking the big 3 of significant leg swelling. I..."
Both Rifampin/Rifabutin and Azithromycin can cause swelling in the legs due to fluid retention.
If this is a new symptom for you, it should be reported to both your pulmonologist (or ID doc) and your primary care provider. Extra caution is indicated if you have a history of heart problems, high blood pressure or blood clots.
Also, if you have recently had a change in any other medications this could be an other cause.
Sue