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@maureenanne

Hi everyone...I had my first Prolia shot on 4/6/23 and had great results for 1st 6 days. On day 7, I woke up and was in so much pain I literally couldn't move. Had to walk with walker for several days, and couldn't leave house for over a week. The list of horrible side effects goes on from there. There is no chance I'll be getting a 2nd shot, and was very worried about the rebound effect of stopping. I did a lot of research on this, and was very happy to find that the rebound thing only starts to take effect after 2nd shot, and 12 months of treatment. It gets worse the longer you are on it. Hope this info helps anyone else who is a one and done with Prolia.

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Replies to "Hi everyone...I had my first Prolia shot on 4/6/23 and had great results for 1st 6..."

I wish we would call a spade a spade. Instead of calling severe reactions side effects, we should call them adverse reactions and report them to the FDA. There us a form on their website to gather important information such as this.

Are you sure it was a reaction to the Prolia? It seems like a long time passed before the reaction. I have never had any reaction to Prolia shots.

Hi, I can personally attest to the fact the rebound effect after being on Prolia for an extended period of time. I went on Prolia in 2019 and stopped abruptly 2021 as it wasn't improving my osteoporosis and I was told by my dentist it could affect my jaw. I had no side affects from the medicine. Unfortunately no one told me the repercussions of going off this medicine cold turkey. My bad for not doing my own research but astonished my doctor who prescribed the medicine, the pharmacy or the location where I received the injection never mentioned how dangerous it would be to go off it.....

Approximately one & half years after I stopped taking Prolia I experienced 5 fractured vertebrae in the span of 6 months all due to stopping this medicine cold turkey. It was beyond painful and I had to take a leave of absence from work for that entire timeframe. After 2 successful kyphoplasty surgeries (the last one was in February 2023), I am completely on the mend and am walking 5 miles a day now. I am now in Evenity and have had 2 injections so far with zero side affects and I feel great!

Hello
My 6 month shot of Prolia ended this week and I am seeing a new rheumatologist-my endocrinologist never informed me of severe side effects of Prolia which I experienced. I was advised actonel but would truthfully like to go the exercise and supplement route. I had chemo 7 years ago and that I believe wore down my bones. I do a tremendous amount of weightbearing exercise- my dexa scan levels are not horrible- beginning stages of osteoporosis.

How are you doing today? Did you ever have any rebound fractures later? I had one shot and I’m done. Need to decide if I need a relay or just get off cold turkey.