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Targeted Treatment Options - Tulsa Pro and MRI-Guided SBRT Options
Prostate Cancer | Last Active: Jun 25, 2023 | Replies (14)Comment receiving replies
Considering the above two options. I’m unfavorable intermediate risk with G7(4+3), 3 lesions rt side, 1 on the left side, Psma pt shows no spread. 63 yrs old, healthy, want to avoid SE’s. Discussed Tulsa pro with Dr. Scionti in FLA (still trying to get Kaiser to send me the disk of my mri and Psma pt scan). Sbrt with Kaiser in South SF, CA. Anyone have either one? Results? SE’s? Regrets? What was the determinative factor that made you choose one over the other? I’m concerned about the small number of men in the TACT trial and the high percentage of cancer missed. Would appreciate your input. Thanks.
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I'm a 4+3, one lesion, localized as well, but older, near 70. I was initially very interested in Tulsa Pro but doctors at both Mayo and Moffitt didn't recommend any targeted therapy due to the intermediate, unfavorable risk profile. Regarding Tulsa Pro, they also cited the fairly high rate of recurrence and the need for close, long term testing including biopsies. I haven't made a final decision yet but at the moment, MRI-Guided SBRT is at the top of my list. Personally, (and I'm not an oncologist) but given your multiple MRI-visible lesions on both sides and your age, I'd be really hesitant to do anything less than whole gland treatment. In regards to SEs, if you haven't already, take a look at the just completed Mirage Clinical Trial.
https://pubmed.ncbi.nlm.nih.gov/36633877/