I do not understand, why are you talking a mastectomy? I had invasive ductile carcinoma with calcifications. The surgeon had the fist sample tested, which showed calcifications in the margin so she had to take more tissue. It came back clean. They closed but sent tissue to FISH for further testing to determine the HER2 2+equivolcal, which came back negative. I have 3 markers which grow the cancer: 100% estrogen, 95% progestogen, HER2 2+ negative. I was told if the calcifications start clumping then that is an indication of possible cancer. Mine were not clumping. But the mass had grown from the size of an eraser 1 year prior to the size of a quarter. I have very dense breast, and I am 76 yrs old. I just finished a 5 day radiation and am waiting for my oncology appointment for the AI medicine. Which will have to be compounded and which i might not be able to take. ? God Bless and take care. my mass was 1.3 cm in size. Stage 1A grade 2