Thanks for the response. My HDL is high as well but unfortunately my LDL went from 128 to 167!! My triglycerides went up too but still in normal range. You are fortunate to have a DO for a doctor. THey look to find the cause of what's going on instead of just telling you to take a pill like so many doctors and mine. I am taking calcuim, vitamin d, vitaman K, magnesium, boron for my bones as well as a biphosphonate (which I don't like), which i will stop if I can ever get off this darn prednisone. I have a video conference meeting with my doctor to discuss this issue and I will bring up diet changes to try first. I'm just nervous that my total cholesterol went from 244 to 301 in just 6 months of ACTEMRA, that's a big increase in a short time. We shall see. Thanks again