When I started with Lialda it did not go well. After a week of taking 2.4 grams daily, I felt horrible. No energy, chills! I thought I had Covid again or maybe the flu. I got tested for both but both tests were negative. I took myself off of Lialda and almost immediately my flu-like symptoms were gone. I asked my GI doctor about the side effects of Lialda but he told me that it was a well tolerated drug. I stayed off of it for about 10 days and then my GI issues got bad so I decided to give Lialda another try. However, I started with a lower dose(i.e 1.6g per day). Much to my surprise, I was able to tolerate it. After about a week of 2 tablets (1.6g), I upped my dose to the three tablets (2.4g) originally prescribed. I have not had any issues with the drug since and it seems to very much help me. The one thing I should also mention is that I drink a minimum of 100 oz of water a day. I believe that also is a big help. I have it in my head that it is helping to constantly flush my system out. I, like everyone else, am still learning what works and what doesn't. I will continue to share but keep in mind what works for me may not work for others. Last thing I would share is that one of my go to foods when my symptoms are bad is peanut butter toast with a bananna. White Bread!