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The impact of Prednisone on A1C

Polymyalgia Rheumatica (PMR) | Last Active: Apr 25, 2023 | Replies (15)

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@annhowledavis

I saw my endocrinologist yesterday. My glucose was 147 on last test. He said that prednisone does impact levels. I am off prednisone now and he recommended a fasting blood test in a few weeks.

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Replies to "I saw my endocrinologist yesterday. My glucose was 147 on last test. He said that prednisone..."

One of the first things my endocrinologist checked was my insulin level. He suspected my insulin level would be high even though I had never been diagnosed with diabetes or prediabetes.
https://physicians.dukehealth.org/articles/even-low-doses-prednisone-creates-insulin-resistance
My endocrinologist was correct because my insulin level was high but my HbA1c and glucose levels were always borderline normal while I was taking prednisone. Nobody had ever checked my insulin level before.

My endocrinologist started me on Metformin because it is suppose to help prevent insulin resistance. He added that I should have been on Metformin during the entire time that I was taking prednisone for PMR. He said a high insulin level was a precursor to diabetes.
https://www.cdc.gov/diabetes/basics/insulin-resistance.html
My endocrinologist said that Metformin will only help with insulin resistance. My endocrinologist thinks that staying off prednisone along with diet and exercise will help more. Now I have to explain to other doctors why I take Metformin when I haven't been diagnosed with diabetes. I think Metformin is helping because now my HbA1C and glucose levels are well within the normal range and aren't borderline anymore. I will ask my endocrinologist to recheck my insulin level when I see him again.