I have been taking an every-4-week injection of Lupron for 21 years. The thing with exercise is do not overdo it. Twice during these 21 years, I engaged in a week-long project that required exhausting effort and resulted in far less than desirable sleep. I lost 15 pounds during each of those projects and the weight was all muscle mass that I could not regain. Once at 175 pounds, I am now 145 pounds. The consequences are unending fatigue. Nevertheless, the benefits of exercise far outweigh the consequences. I don't think that I would be alive today without it.