I agree. I am one year out from my second round of LC, and have PEM, POTS, and all the other vague symptoms that are autoimmune mediated. I was an avid exerciser, who was running, and doing HIIT classes 5-7 days a week. I am now back to where I was except having to really manage fluids and electrolytes. Yesterday was a bad day. I was already dehydrated from having a few drinks with friends the night before. I did not hydrate prior to my 5 mile run, and paid for it the rest of the day. After several rounds of liquid IV and rest, I felt much better. It will be lifelong I am afraid.