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Hot flashes 3 months after Eligard?

Prostate Cancer | Last Active: Apr 13, 2023 | Replies (5)
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@maxvt

After a 3-month injection of Lupron, I had hot flashes day and night. My face turned noticeably red and I would pick up something, anything, to fan myself.

With some research, I found an article detailing a man my age with prostate cancer, a Lupron injection and hot flashes. His doctor prescribed Venlafaxine, an antidepressant, which relieved the hot flashes.

My PCP switched my antidepressant to Venlafaxine, 37.5 mg 2 times per day. It worked!

Here’s the article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184578/

Good Luck!

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Replies to "After a 3-month injection of Lupron, I had hot flashes day and night. My face turned..."
ssaftler | @ssaftler | Apr 12, 2023

Thanks for the note. Sorry you had the side effects from the start, but happy that you were able to get quick relief.
I was sort of expecting the hot flashes from the outset. However, after the Eligard (alternate drug for Lupron, so I was told) shot, I had no hot flashes or night sweats at all. Nothing after the BT, and nothing through the IMRT treatments. It was only on this Monday and Tuesday mornings that I actually woke up in a sweat. Also noticed my undershirt was damp this morning, but I must have slept right through it. I might not have noticed it if I hadn't had to get up to go to the bathroom (still at least twice per night) around 3AM, since I was dry when I finally woke up.
So, here I am, a full week removed from the last treatment, and now I get the night sweats? I'm expecting a follow-up call from my RO's office today, so I will mention it to them to see if anything can or needs to be done. Perhaps the hot flashes are a side effect of the Eligard wearing off and my testosterone returning to normal?
Hope you are doing well with your therapy or feeling good if you've completed it.

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