Methylsulfonomethane. It is a dietary supliment that gives a supply of sulfur to the diet which is in many reactions in the metabolism. There is much about it on the net and requires no script. It has no known toxic dose and no side effects that I can descern. I take 3 grams every morning with juice and use the same one I buy for my horses. I have used it for years for their arteritis and for dogs also. You can get it for people, too. It has been shown to lower IL6. As to LDN, I use it currently as it lowers my "non-moving" pain and healed my small intertine wish was full of inflamation from Crohn's. How much of the pain was from PMR, it is hard to say. But worth a try and side effects are usually vivid dreams.