Good morning, I was diagnosed with MBC ER/PR+ and HER2- back in 2019. At that time, it was in my left breast, 2 1/2 of my lymph nodes and 2 areas on my vertebrae. I was considered "low volume" back then, as my CEA-15 tumor markers were only 37. I was immediately put on Ibrance, Letrozole and Lupron injection and was declared NEDS in 2020. I was on the maximum dosage and requested my doctor lower my dosage since I was NEDS, and she refused stating that my body could handle it. Fast forward, 2021, it came back in my left breast as a mutation (ESR1 & Mtor). My doctor was more concerned with the ESR1 mutation and suggested I have my ovaries removed, which I did, but also switch my hormonal blockers to Faslodex. Now mind you, an ESR1 mutation develops when the cells become resistant to hormonal blockers. Why put me on another one when I have developed a mutation is beyond me, but I was put on Faslodex. Let me preface that I was taken off of Ibrance, Letrozole, Exemestane and the Lupron Injection. During the time on Faslodex, I had severe pain in my left hip and had 3 lesions there. Ended up with a complete hip replacement. Then it traveled to 3 areas on my back and 3 lesions in my liver. So now I am on Xeloda, a targeted chemo pill. I am not a fan of chemo, but so far, I'm doing okay on it. Let me also add that I do so much with alternative treatments as well to try to keep the volume low.