I am new to the Mayo Support groups and was very excited to see a post titled "ALENDRONATE." I was diagnosed with osteoporosis (doc said I am in the bottom .5%) July 2022. I had a TKR replacement scheduled for the end of August 2022, so I was instructed to wait until at least 6 months post op to begin any treatment. The surgeon who did my knee replacement replacement said my bones were mush and crumbling, indicating if I had another waited another 2 weeks, the part in my knee would have come through my shin. I had no idea osteoporosis was so dibilating. I have had so many health issues since recovering from late stage 3 breast cancer 10 years ago, now I see they can be attributed to osteo.
But back to the Alendonate. I began the medication first week of February this year. I got so sick I was bedridden. It was just like having Chemo again. I felt like I was dying. I called my Internal Medicine doctor who gave me the RX, and he said to take it for a month to get acclimated to it. Horrible. I was in bed for 5 weeks. Not until the 6th week was I able to get up and about and join the living. I'm still getting my strength back. I've been wanting to post here, but for some reason have hesitated. I am hoping to hear if anyone else has had this type of allergic reaction to Alendronate.
I understand this doesn't help you and doesn't anwer your question about Alendronate, sorry.
FYI I am a 65 year old female breast cancer survivor, a recovering alcoholic (16 years!), an ex-smoker with an assortment of health problems. Thanks for listening to anyone reading.

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