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PMR and Methotrexate

Polymyalgia Rheumatica (PMR) | Last Active: 1 day ago | Replies (200)

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@maggie14

I have just gone on 10 mg. of methotrexate morning and evening once a week. Sure hope it will be effective. I guess it can take 6 - 8 weeks.

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Replies to "I have just gone on 10 mg. of methotrexate morning and evening once a week. Sure..."

Hello- I was diagnosed with PMR 12/2021 by my Primary care provider. She started me on 15mg of Predisone daily and after 6 month reduced to 10mg. Sometime summer of 2022 taper to 7mg and stayed there until I was referred to a Rheumatologist, Sept 2022. He started me on Hydroxychloroquine 200 mg twice a day. Then in November 2022 he added Methotrexiate 20mg weekly, continued with 7mg of prednisone. Feb 2023 began to reduce Predisone by 1mg a week and now I’m off Pred and still on the other two. My ESR is high normal and CRP still elevated. The rheumatologist is not convinced I have PMR but Inflammatory Polyarthritis. I can tell you that I am not convinced that the other two meds are helping but I can say my pain score on the predensone (2mg) and the other two drugs was about a .5 out of 10. Now w/o Predisone for about 5 days it is at a 3. I do take extra strength Tylenol which helps.

I will continue with the hydroxycloraquine and methrotrexate but I’m not sure why I need both. If someone can shed some light on that subject, I would appreciate it.

Thanks!
Maj