I've thought about stopping because it may be doing more harm than good, but I hate to take a chance on it. My oncologist even told me a year ago that she didn't know if I needed it. Now we know it's no longer hormone positive but I'm still on it. I've heard people say that this drug can cause other cancers?? That's why I'm concerned, I can deal with the joint pains. I've now been on it for almost 2 years. There are no big facilities near me unless I travel. I am certainly going to bring it up again on next appointment.