Check out my posts for more on oral Ketamine. I have been taking Ketamine since March 2022. Recently I began taking it for intolerable shoulder and neck pain. On the advice of my doctor, I take Asprin a half hour before the 600mg of Ketamine (it is tablets that melt under your tongue). I have felt some relief. Ketamine was a life changer for my 40+ years of TRD and CPTSD. It is worth trying anything if you have fought Depression since 18 years of age. I am now 61.

I have continued taking Zoloft with the Ketamine. I still am at this time. At one point I forgot 2 days/ doses in a row last May and I fell deep back into depression and became very suicidal. Only because I had no energy to get up off the couch I did not proceed with killing myself. Once the level of Sertraline/ Zoloft was back to usual my depression abated once again. I hoped to get off Antidepressants. That does not appear to be a possibility for me.