My experience is somewhat different in important respects. Primary Aldosteronism was an accurate but belated diagnosis, thanks to my nephrologist and endocrinologist who weighed in after several years of treatment for hypertension by specialists in other branches of medicine. Spironolactone was my favored medication a few years ago, but I had to drop it because of its known ability to aggravate Gynecomastia (male breast growth) which affected my father and resulted in a genetic vulnerability to breast cancer. Three young women in my father's family tree inherited his genetic variant and were treated for breast cancer. Clearly, Spironolactone was an unacceptable risk for me. After several years of treating my hypertension with a variety of well-known medications, tests last year showed that aldosteronism was an important factor. Eplerenone was prescribed and appears to be effective in helping to control my hypertension, although we're still in a low-dose trial of only 25mg per day. This caution arose because of my inherited kidney problem of sloughing off potassium, which had been addressed with a potassium-sparing diuretic (Amiloride) for several years. Since Eplerenone also has diuretic impacts, my medical team is concerned that it might supplement my regular diuretic and increase potassium in my system, leading to hyperkalemia which can be a severe condition. So far, that has not been a problem, but a decision to increase the dosage of Eplerenone has been delayed until a balance in potassium is documented as enduring later this year. As to the cause of my Primary Aldosteronism, I have a tumor on one adrenal gland, but after several years of watching it and testing it, my medical team believes its impact is small enough that surgery is not necessary because Eplerenone is a sufficiently effective medication in my case. Martin