Lower dose of Exemestane (<25 mg)

Posted by lauranc @lauranc, Aug 17, 2021

I started to take Exemestane to avoid some of the side effects that I had from Letrazole that made me extremely fatigued. Even though I feel better with Exemestane I do have joint pains. I wanted to know if somebody knows of clinical trials to study doce reduction. Could I try a lower dose and still have the benefit of the drug but with lower side effects? If you know of any trials or doctors that are working with a doce reduction please let me know

Interested in more discussions like this? Go to the Breast Cancer Support Group.

dlmdinia | @dlmdinia | Apr 5, 2023

I just got an email regarding trials on lower doses of exemestane (which I was on only briefly because my insurance doesn't cover it).
Because I've seen recent posts regarding dosages of other AI's, I decided to search similar posts for exemestane and thought I'd share.
I hope it's helpful even though this thread is not recent. https://www.cancertherapyadvisor.com/home/cancer-topics/breast-cancer/breast-cancer-exemestane-given-3-times-week-is-noninferior-daily-dosing/

evamariematiszik | @evamariematiszik | Feb 19 9:28pm

In reply to @auntieoakley "I had to go find this because I just read it a few days back, but..." + (show)

Thank you so much. This gives me hope I can continue. Side effects meant I was going to give up.

Chris, Volunteer Mentor | @auntieoakley | Feb 20 12:17am

I hope you can find some tips and tricks to stay on course. Side effects really stink and most treatments have them. It helps me to remember that cancer has a couple of really nasty side effects too. Which is meant to be a bit of dark humor for cancer survivors.
If the side effects are just too awful, are you comfortable asking your doctor to try something different?