Have never tried the new legal CBD/TCH (yet), but researching supplements for joint health and pain, I learned that MSM and Glucosamine had anti-imflamatory effects (besides their primary goals promoting joint health). I am relatively pain free, but when I feel some joint pain (big toe) in the day, I will pop an extra MSM and it does as well as acetaminophen. I've determined there is no risk, so I'll continue the experiment. For what its worth--realizing that variable joint aches are a far CRY from arthritis.