I have had both. Chemo is a bit debilitating but do-able. I had a port inserted and took the chemo that way. You will feel absolutely wiped out. I never had much nausea but did take the anti-nausea pills they gave me.

Radiation is painless, but the sessions do build up, so it has become a bit painful towards the end. I have not had to take pain killers so, again, it is manageable. I think I have had over 20 sessions and take chemo pills every day. I have 3 sessions to go, then we will see the result. I will say that I feel quite positive as I don't feel any pain from the cancer presently.