I have been off Eligard since June 2022. I am off Xtandi too. The fatigue improves after discontinuing Eligard. I took it for so long due to having a very aggressive cancer. Gleason 9. 24 months for your husband may be enough but his urologist decides that. Some people are off and on this drug. Best for your husband. He needs to stay positive. It’s a long and difficult road but it may lead to a beautiful destination.