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@stageivsurvivor

These are some links describing pro-active measures to prevent/lessen peripheral neuropathy-
NEUROPATHY PREVENTION WHEN TAKING FOLFIRINOX/ICING

https://www.uspharmacist.com/article/ice-chips-prevent-hyperalgesia-with-oxaliplatinhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810270/https://learn.colontown.org/topic/managing-neuropathy-and-cold-sensitivity/https://ascopubs.org/doi/abs/10.1200/JCO.2020.38.15_suppl.e16140https://paltown.org/icing/https://letswinpc.org/research/more-research-needed-for-neuropathy/

My oncologist used an alternate dosing cycles of six cycles Folfirinox followed by six cycles of 5-FU with Leucovorin and then repeat again with six of Folfirinox until a total of 46 cycles were completed (24 of Folfirinox 22 of 5-FU/Leucovorin). This lessened the impact of Oxaliplatin on the peripheral nerves and the neuropathy did resolve after several years.

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Replies to "These are some links describing pro-active measures to prevent/lessen peripheral neuropathy- NEUROPATHY PREVENTION WHEN TAKING FOLFIRINOX/ICING..."

I have ordered cold gloves & socks to wear during the infusions however I am concerned about when the not being able to touch anything cold from the fridge or freezer begins. Like how long after the infusion ends? I have no idea what to expect.

I also plan to use Kali Phosphoricum 30c & Hypericum 30c homeopathic pellets plus CBD cream infused with essential oil to more easily absorb into the skin. I am now hearing that all of these are very beneficial. Beats taking Gabapentin, yet another drug, which doesn’t apparently work.

The article on managing the neuropathy is most helpful. I had 10 or 11 oxaliplatin treatments and wound up with significant nerve damage. I list most all proprioception and the muscle atrophy was obvious from the nerve damage. My hands looked like my mother’s who lost nerves in her hands from polio. I stopped the oxaliplatin almost a year ago and continued with 5fu, campostar, and leucovorin. At the PET scan in October and again in February my cancer showed no growth. I am continuing on chemo and my Ca19-9 is down to 16. Do you know of any protocols as to how long to stay in chemo. I have spread out from every 2 weeks to every 3 weeks with the Ca19-9 continuing to slowly drop. Thank you fir any insight you can provide. My cancer is in operable. All detected possible metastasis areas are resolved.