One thing to add: because oxaliplatin is neuotoxic to peripheral nerves, Dr. Shah did alternating doses of 6 cycles Folfirinox followed by 6 cycles of just 5-FU with Leucovorin. I continued responded well with all tumors shrinking on the “resting cycles” of 5-FU with Leucovorin. This likely was the reason my neuropathy was not severe and eventually resolved after a number of years. I had a total of 46 cycles with 24 of Folfirinox and 22 of 5-FU/Leucovorin.