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← Return to 12 months free of disease with clear CT scans: What is next?
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12 months free of disease with clear CT scans: What is next?
Pancreatic Cancer | Last Active: Jun 6, 2023 | Replies (42)Comment receiving replies
Hello & congrats on being cancer free! Just wondering if you have any lingering side effects, such as peripheral neuropathy, from the Oxiliplatin? Any idea how to prevent that or what helps if one contracts it during the standard 12 rounds of the 5-FU regimen? I’m starting on it on 4/10 and have heard so many neuropathy horror stories that I am terrified more of that than the cancer itself! A friend had this regimen for colo-rectal cancer. He is cured from the cancer but 5 years later still cannot feel his toes.
Thank you!
Replies to "Hello & congrats on being cancer free! Just wondering if you have any lingering side effects,..."
These are some links describing pro-active measures to prevent/lessen peripheral neuropathy-
NEUROPATHY PREVENTION WHEN TAKING FOLFIRINOX/ICING
https://www.uspharmacist.com/article/ice-chips-prevent-hyperalgesia-with-oxaliplatin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810270/
https://learn.colontown.org/topic/managing-neuropathy-and-cold-sensitivity/
https://ascopubs.org/doi/abs/10.1200/JCO.2020.38.15_suppl.e16140
https://paltown.org/icing/
https://letswinpc.org/research/more-research-needed-for-neuropathy/
My oncologist used an alternate dosing cycles of six cycles Folfirinox followed by six cycles of 5-FU with Leucovorin and then repeat again with six of Folfirinox until a total of 46 cycles were completed (24 of Folfirinox 22 of 5-FU/Leucovorin). This lessened the impact of Oxaliplatin on the peripheral nerves and the neuropathy did resolve after several years.
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I’ve been through 8 rounds of chemo. Number 9 was held back because my bloodwork came back showing a low count. It has been nice for third week after chemo. The peripheral neuropathy has subsided from my handsome feet. I still have it in my mouth.