PSA level after Proton Therapy

Posted by bandit11 @bandit11, Mar 27, 2023

Had 29 sessions of Proton Therapy about 10 months ago. Was unfavorable intermediate with PSA level of 8.6 and chose not to do ADT. Curious about others post treatment ADT in similar circumstances. My first post treatment PSA was 2.8 at 3 months and 2.5 at 6 months. Radiologist said well within expectations as long as trend continues downward. Next PSA test at one year.

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It would be helpful if replies were relevant to question asked.

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@mikewo

HIFU is used to treat localized prostate cancer and I considered it but the expert at Mayo said I had too much calcifications in my prostate to attempt it successfully. He said he did not want me to be his guinea pig. HIFU only targets the lesion and margins and not the whole prostate.

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Please explain calcification is as it relates to the prostate and what causes it if your doctor explained it

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I am not positive as to what causes it and the doctor did not explain it other than to say it does not allow the high intensity ultrasound waves to pass thought it like normal prostate tissue. That does not give him the certainty he felt necessary to destroy the cancer completely without it returning in my case.

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March 2010 proton radiation at Loma Linda-2.5 months with treatment every morning. Initial diagnosis at: PSA: 647; Gleason 3 plus 3 with slow-growing cancer in the right lob of the prostate. Between post-radiation and 2016, PSA remained below 1.0 (usually below .5 initially). I had now after effects of radiation except by Friday I was somewhat tired. In fact, while at Loma Linda, I stayed at March AFB quarters and played racquetball most afternoons.. Then in 2018, PSA began to rise now at 4.36. Had MRO two weeks ago and the diagnosis was the possible return of cancer. The cell structure is rated between 1 and 5 with five highly likely.

But, reading my scanning results from Loma Linda whereupon they identify and target the prostate were several comments about calcification. Calcification can resemble cancer in terms of cell formation. So what to do. I am going to review and test the PSA every six months; have written to my former doc at Loma Linda for comments. In the state; ask questions and second opinions..try and avoid surgery if possible. Lastly, proton radiation can be expensive. The 2.5 months at Loma Linda, I had to pay for housing which was not that much, rental car and food expenses. At that time, each morning proton experience was near $4000.00. State of the art medical care costs money.

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