Hi Ray - The only prescription medicine I take for PN is Gabapentin. It helps minimize nerve pain discomfort and the heat/cold intolerance I can get in my hands and feet. Doctors like to advise depression/anxiety meds, but I can’t afford the dopiness side affects and the increased risk of more imbalance & falling, so I try to do positive mind exercises instead. I’ve held back on ALA because I get low blood sugar and my last Neurologist didn’t know if it was safe. I have a new Neurologist appt in my new state next week & will ask her knowledge; I’ll also ask about an MRI that I’ve never had in my 6+ yrs with PN, so congrats to you for getting one scheduled! I take B12 and when I stopped it once, felt bad after a few days and restarted it. I take Magnesium too. I liked having 5 Accupuncture treatments I had- it’s hard to describe the relaxation my nerves and mind seem to get from it, but my big help is the PT; continue as much as you can unless you think you’re disciplined enough to keep the exercises up on your own. Even if you do, I’d get a PT follow up once in awhile. This forum has given me a lot of help on lotions, supports, shoes etc. keep reading, stay positive, and best of luck!!!