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New antidepressant: Has anyone tried Auvelity?

Depression & Anxiety | Last Active: Mar 6 7:45pm | Replies (61)

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@efisk3

Hi there, I'm only 25 but I have a very similar experience. I did 36 TMS treatments with pretty much no improvement, tried every drug under the sun (probably 20+ meds, including the Trintellix and Wellbutrin) and 15 years of therapy. Wellbutrin gave me a tiny bit of improvement (My depression is a 9 without it, and probably a 7-8 with it) but nothing to write home about. Spravato was my next course of action until learning about Auvelity. I have been on Auvelity for a little over a week, and I have already started to see results. I haven't felt this happy, like.... ever. I've struggled with depression since I was VERY young (signs starting at age 5 or 6) and been on medication since age 10 or 11. I am also on disability and get it covered, thank goodness. It's worth trying.

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Replies to "Hi there, I'm only 25 but I have a very similar experience. I did 36 TMS..."

Wow. Your story caught my eye. I am twice your age and have suffered from depression for most of my life. I also have tried, I believe in the neighborhood of 19-20 medications, two rounds of TMS and some other procedures. Yet here I am, now on disability and struggling with depression still.
My new psychiatrist is “washing “ me off of my meds as I was over medicated with no results. I am now down to just 10 mg trintellix and titrating off of that. The ultimate goal was to try Auvelity. We went through a lot with our insurance to get it- I did secure a prescription. I took it for 3 days and it caused extreme panic. I had to stop it.
But as I read your good results from it and I long to be happy, I wonder if I should try it again. Did you have any increased anxiety? Do you take it with food or at an exact time of day? In other words do you have to be more careful with it than other psychiatric medications?
Any details you could share I would appreciate. Also there have been many drugs over the years that work initially for me but within a very short time they stop working completely. Have you had this experience?
I hope Auvelity continues to make a big difference in your life! Treatment resistant depression is a huge struggle and if you are able to find relief it is a huge gift!