@carsonann and @seanmacbeth, There is a discussion on the protocol that you might want to join here:
-- Have you tried the new Protocol 525 product for neuropathy relief?:
https://connect.mayoclinic.org/discussion/have-you-tried-the-new-protocol-525-product-for-neuropathy-relief/.

I've been taking the protocol since 2016 and feel it's helped me but I only have numbness and no pain with my neuropathy. It seems to have slowed or stopped the progression with my neuropathy but I haven't had any additional EMG tests to see if there has been an improvement. Part of my problem is that I have to wear compression socks for lymphedema and they always make my legs feel a little tingly from being squeezed all day long. Lately I can feel the bottom of my feet again so that is good enough of a reason for me to continue using the protocol.