Have taken ALA synthetic for several months now with no results, so have been researching the difference between that and R-ALA (Alpha Lipoic Acid) and will start soon. In my research I discovered something called The Protocol 525, a supplement (see site for ingredients). Very promising results from testimonials. They use high therapeutic doses of R-ALA, certain
B vitamins and Hemp Seed Oil. Expensive -over $200/month. They have a FB group to join. The ALA recommended dose is twice what I've been taking (600). Would like to have comments from anyone in Mayo group who knows of it or has tried it. It might be worth the cost, because putting together every ingredient in a stack would perhaps be around that amount and it's hard to find a B group without B6, the one B not included because of toxicity above 100mg daily. I had my vitamins checked last year and found I had a toxicity level of B6. It can actually cause neuropathy at higher levels! Curious to know if this is a breakthrough or just another false hope!