I’m planning to ask my physician about Tymlos since my recent DEXA results had worsened by almost 10% on hip area. It’s not horrible at -2.2 but the 10% decease is definitely concerning. Had to stop Prolia which seemed to be helping as developed jawbone necrosis after taking for many years. I haven’t heard of the oral medication, what class of drug is it as cannot take bisphosphonates either due to both an allergic reaction & they also have the jawbone necrosis side effect

I was diagnosed @ Mayo with severe osteoporosis of the spine. The doctor suggested Evenity. The black box warning scared me to death. I was on an estrogen patch after an hysterectomy for thirty years. No osteoporosis at that time. Then had knee replacement surgery and was told by surgeon to remove patch due to clotting issues. I am about to go back on the patch. I know it doesn’t rebuild bones, but not enough research has been done on Evenity. Would alendronote be a drug I could use? Or do I have to take a stronger drug prior to the one you take on Mondays?