Hello, I've suffered constipation since many years ago, and I HAVE to go every day, if not, I know I'll be screaming of pain, so what has really really worked for me, is eating a good portion of Papaya 3 times a day, it's natural and If you don't like the taste (which I do like) you can mix it with yogurt, or with lime and sugar, but remember, you HAVE to be consistent! once in a while if I forget or run out of it, I have a full 45 mg of milk of magnesia, good luck!