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@bruningk

I was diagnosed in the fall of 2016. I did Transurethal Hyperthermia in Germany March 2017. In March 2019 I did Radiation. Now after Pet scan confirmation I’m being treated again, currently on Lupron. I know from my research hormone therapy is needed right now but also read my cancer can/will become resistant to this treatment and continue to grow. Once it becomes Metastatic, it’s over for me and cannot be cured. My question for the group is, why not try chemo now instead of waiting until it spreads and can’t be cured? Does localized prostate cancer not respond well to Chemo?

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Replies to "I was diagnosed in the fall of 2016. I did Transurethal Hyperthermia in Germany March 2017...."

There are various studies about the use of chemotherapy early in the treatment, look for doublet and triplet therapy.

From my laymen's understanding, there are some PCa cells which are adaptive and do not respond (die...) to the low testosterone environment created by the use of monotherapy, in your case Lupron. Those cells may however, be "killed" by chemotherapy.

Discuss with your medical team, if you are physically and medically able to go through doublet or triplet therapy, it could be n option for a more durable remission.

Kevin