My husband has stage 4 metastatic prostate cancer too, and received his 1st Pluvicto treatment last Tuesday. He has been in extreme pain in his leg(shin) and hip (where he had a hip replacement about a 3 years ago.) We know he has some cancer in his bone in the hip but not sure about the shin. He has had an terrible headache off and on throughout the days. Anyone have any similar side effects and what are you using to help with them?