Hi @1morgan, welcome. I moved your question about rising levels of CA 125 to this existing discussion:
- - CA-125 Results Went Up: Should I be concerned? https://connect.mayoclinic.org/discussion/ca-125-results-rose/

I did this so you can read previous posts and connect with members like @stparker54 @starko @miriam57 @odette @carole2022 @cctoo @smalayman4016 @drterry @egins1208 @chrissiebee and others.

From Mayo Clinic:
"Rising CA 125 levels MAY indicate that ovarian cancer has come back after treatment. Regular monitoring of CA 125 has NOT been shown to improve outcomes for those with ovarian cancer and may lead to additional and unnecessary rounds of chemotherapy or other treatments."

Usually further testing and monitoring are necessary to confirm what is going on. Has your oncologist suggested further testing?