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CA-125 Results Went Up: Should I be concerned?

Gynecologic Cancers | Last Active: Jun 9 2:39am | Replies (51)
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@1morgan

two years ago was diagnosed with stage 4 ovarian cancer, went through surgery and then Chemo its been a year and 4month in remission. In Feb my CA 125 was 13.5 in March first week my numbers went up to 723. CT shows no signs of anything two weeks later my CA 773. Should I wait for signs or get a PET done? My doctor says we might just be treating a number.
any insite on this would be grateful

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Replies to "two years ago was diagnosed with stage 4 ovarian cancer, went through surgery and then Chemo..."
Colleen Young, Connect Director | @colleenyoung | Mar 17, 2023

Hi @1morgan, welcome. I moved your question about rising levels of CA 125 to this existing discussion:
- - CA-125 Results Went Up: Should I be concerned? https://connect.mayoclinic.org/discussion/ca-125-results-rose/

I did this so you can read previous posts and connect with members like @stparker54 @starko @miriam57 @odette @carole2022 @cctoo @smalayman4016 @drterry @egins1208 @chrissiebee and others.

From Mayo Clinic:
"Rising CA 125 levels MAY indicate that ovarian cancer has come back after treatment. Regular monitoring of CA 125 has NOT been shown to improve outcomes for those with ovarian cancer and may lead to additional and unnecessary rounds of chemotherapy or other treatments."

Usually further testing and monitoring are necessary to confirm what is going on. Has your oncologist suggested further testing?

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